[PDF][PDF] Role of the FtsA C Terminus as

M Krupka, EJ Cabré, M Jiménez - 2014 - researchgate.net
… activates a switch favoring the polymerization of FtsA and at … helix at its C terminus to become
attached to the membrane. … the FtsA C terminus, besides mediating the association of the …

Assembly and architecture of Escherichia coli divisome proteins FtsA and FtsZ

JJ Morrison, J Conti, JL Camberg - Journal of Biological Chemistry, 2022 - ASBMB
… While FtsZ is known to function as a dynamic, polymerizedFtsA polymerization is coregulated
with FtsZ polymerization. … FtsZ polymerization state is coordinated with FtsA, and the FtsA/…

Escherichia coli FtsA forms lipid-bound minirings that antagonize lateral interactions between FtsZ protofilaments

M Krupka, VW Rowlett, D Morado, H Vitrac… - Nature …, 2017 - nature.com
… along with the FtsA-binding peptide from the C terminus of FtsZ (… the polymerizing domain
and the FtsA-interacting C-terminal … we propose prevents this switch towards FtsZ bundling and …

Roles of the essential protein FtsA in cell growth and division in Streptococcus pneumoniae

A Mura, D Fadda, AJ Perez, ML Danforth… - Journal of …, 2017 - Am Soc Microbiol
… In this study, we investigated the role of FtsA in S. pneumoniae (pneumococcus), a
clinically relevant human pathogen and a reference species to study cell division in Gram-positive …

Escherichia coli ZipA organizes FtsZ polymers into dynamic ring-like protofilament structures

M Krupka, M Sobrinos-Sanguino, M Jiménez, G Rivas… - MBio, 2018 - Am Soc Microbiol
FtsA competitor for FtsZ polymers because of their common binding site at the FtsZ C terminus
… of ZipA on FtsZ protofilaments, including its role in polymer bundling. In contrast to the …

The keepers of the ring: regulators of FtsZ assembly

C Ortiz, P Natale, L Cueto… - FEMS microbiology …, 2016 - academic.oup.com
Polymerization and attachment of FtsA to the membrane is … switch of the amphipathic helix
located at the C-terminus of … may result from the dual function that FtsA exerts on FtsZ, first …

Peptide linkers within the essential FtsZ membrane tethers ZipA and FtsA are nonessential for cell division

KM Schoenemann, DE Vega… - Journal of Bacteriology, 2020 - Am Soc Microbiol
… To investigate whether the postulated ∼20-residue linker is important for the function of
FtsA… derivatives (fused to GFP at their C termini) into the thermosensitive zipA1 background to …

De Novo Synthesis of Basal Bacterial Cell Division Proteins FtsZ, FtsA, and ZipA Inside Giant Vesicles

T Furusato, F Horie, HT Matsubayashi… - ACS synthetic …, 2018 - ACS Publications
… N and C terminal sfGFP-fused FtsA showed clear membranepolymerization and the membrane
recruitment of FtsZ by FtsA, … FtsZ and the membrane tethering function of FtsA and ZipA. …

Building the Bacterial Divisome at the Septum

JJ Morrison, JL Camberg - … Protein Complexes V: Structure and Function, 2024 - Springer
polymerization of FtsA on the lipid membrane may impact division, and we will discuss this
and other ways that division in bacteria is regulated through FtsZ and FtsAswitch that occurs …

Coregulated assembly of actin-like FtsA polymers with FtsZ during Z-ring formation and division in Escherichia coli

JJ Morrison, J Conti, JL Camberg - bioRxiv, 2021 - biorxiv.org
… regulating FtsA function, we characterized a truncated E. coli … FtsA polymerization is
coregulated with FtsZ polymerization, … that membrane association is critical for FtsA enzyme …