S-(−)-Oleocanthal Ex Vivo Modulatory Effects on Gut Microbiota

MH Qusa, KS Abdelwahed, RA Hill, KA El Sayed - Nutrients, 2023 - mdpi.com
Compelling evidence points to the critical role of bioactive extra-virgin olive oil (EVOO)
phenolics and gut microbiota (GM) interplay, but reliable models for studying the
consequences thereof remain to be developed. Herein, we report an optimized ex vivo fecal
anaerobic fermentation model to study the modulation of GM by the most bioactive EVOO
phenolic S-(−)-oleocanthal (OC), and impacts therefrom, focusing on OC biotransformation
in the gut. This model will also be applicable for characterization of GM interactions with …

[PDF][PDF] S-(−)-Oleocanthal Ex Vivo Modulatory Effects on Gut Microbiota. Nutrients 2023, 15, 618

MH Qusa, KS Abdelwahed, RA Hill, KA El Sayed - 2023 - researchgate.net
Compelling evidence points to the critical role of bioactive extra-virgin olive oil (EVOO)
phenolics and gut microbiota (GM) interplay, but reliable models for studying the
consequences thereof remain to be developed. Herein, we report an optimized ex vivo fecal
anaerobic fermentation model to study the modulation of GM by the most bioactive EVOO
phenolic S-(−)-oleocanthal (OC), and impacts therefrom, focusing on OC biotransformation
in the gut. This model will also be applicable for characterization of GM interactions with …
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