SARS-CoV-2 mediated neuroinflammation and the impact of COVID-19 in neurological disorders

N Amruta, WH Chastain, M Paz, RJ Solch… - Cytokine & growth factor …, 2021 - Elsevier
SARS-CoV-2 is a novel coronavirus that severely affects the respiratory system, is the cause
of the COVID-19 pandemic, and is projected to result in the deaths of 2 million people
worldwide. Recent reports suggest that SARS-CoV-2 also affects the central nervous system
along with other organs. COVID-19-associated complications are observed in older people
with underlying neurological conditions like stroke, Alzheimer's disease, and Parkinson's
disease. Hence, we discuss SARS-CoV-2 viral replication and its inflammation-mediated …
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