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[HTML][HTML] SARS-CoV-2 neutralization resistance mutations in patient with HIV/AIDS, California, USA

SA Hoffman, C Costales, MK Sahoo… - Emerging Infectious …, 2021 - ncbi.nlm.nih.gov
SA Hoffman, C Costales, MK Sahoo, S Palanisamy, F Yamamoto, CH Huang, M Verghese…
Emerging Infectious Diseases, 2021•ncbi.nlm.nih.gov
We report persistent severe acute respiratory syndrome coronavirus 2 infection in a patient
with HIV/AIDS; the virus developed spike N terminal domain and receptor binding domain
neutralization resistance mutations. Our findings suggest that immunocompromised patients
can harbor emerging variants of severe acute respiratory syndrome coronavirus 2.
Abstract
We report persistent severe acute respiratory syndrome coronavirus 2 infection in a patient with HIV/AIDS; the virus developed spike N terminal domain and receptor binding domain neutralization resistance mutations. Our findings suggest that immunocompromised patients can harbor emerging variants of severe acute respiratory syndrome coronavirus 2.
ncbi.nlm.nih.gov
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