STV1, a ribosomal protein, binds primary microRNA transcripts to promote their interaction with the processing complex in Arabidopsis
MicroRNAs (miRNAs) are key regulators of gene expression. They are processed from
primary miRNA transcripts (pri-miRNAs), most of which are transcribed by DNA-dependent
polymerase II (Pol II). miRNA levels are precisely controlled to maintain various biological
processes. Here, we report that SHORT VALVE 1 (STV1), a conserved ribosomal protein,
acts in miRNA biogenesis in Arabidopsis. A portion of STV1 localizes in the nucleus and
binds pri-miRNAs. Using pri-miR172b as a reporter, we show that STV1 binds the stem-loop …
primary miRNA transcripts (pri-miRNAs), most of which are transcribed by DNA-dependent
polymerase II (Pol II). miRNA levels are precisely controlled to maintain various biological
processes. Here, we report that SHORT VALVE 1 (STV1), a conserved ribosomal protein,
acts in miRNA biogenesis in Arabidopsis. A portion of STV1 localizes in the nucleus and
binds pri-miRNAs. Using pri-miR172b as a reporter, we show that STV1 binds the stem-loop …
STV1, a ribosomal protein, binds primary microRNA transcripts to promote their interaction with the processing complex in Arabidopsis.
LSJ Li ShengJun, LK Liu Kan, ZSX Zhang ShuXin… - 2017 - cabidigitallibrary.org
MicroRNAs (miRNAs) are key regulators of gene expression. They are processed from
primary miRNA transcripts (pri-miRNAs), most of which are transcribed by DNA-dependent
polymerase II (Pol II). miRNA levels are precisely controlled to maintain various biological
processes. Here, we report that SHORT VALVE 1 (STV1), a conserved ribosomal protein,
acts in miRNA biogenesis in Arabidopsis. A portion of STV1 localizes in the nucleus and
binds pri-miRNAs. Using pri-miR172b as a reporter, we show that STV1 binds the stem-loop …
primary miRNA transcripts (pri-miRNAs), most of which are transcribed by DNA-dependent
polymerase II (Pol II). miRNA levels are precisely controlled to maintain various biological
processes. Here, we report that SHORT VALVE 1 (STV1), a conserved ribosomal protein,
acts in miRNA biogenesis in Arabidopsis. A portion of STV1 localizes in the nucleus and
binds pri-miRNAs. Using pri-miR172b as a reporter, we show that STV1 binds the stem-loop …
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