[HTML][HTML] Safety and efficacy of autologous skeletal myoblast sheets (TCD-51073) for the treatment of severe chronic heart failure due to ischemic heart disease
Y Sawa, Y Yoshikawa, K Toda, S Fukushima… - Circulation …, 2015 - jstage.jst.go.jp
Background: Poor survival outcomes for patients with severe heart failure (HF) and the
donor shortage for heart transplantation warrant the development of myocardial
regenerative therapy. We performed a multicenter, phase II study to evaluate the safety and
efficacy of autologous skeletal myoblast sheets (TCD-51073). Methods and Results: In 3
study sites, we enrolled 7 patients with severe chronic HF due to ischemic heart disease
despite maximal therapy, all of whom underwent transplantation of TCD-51073. No serious …
donor shortage for heart transplantation warrant the development of myocardial
regenerative therapy. We performed a multicenter, phase II study to evaluate the safety and
efficacy of autologous skeletal myoblast sheets (TCD-51073). Methods and Results: In 3
study sites, we enrolled 7 patients with severe chronic HF due to ischemic heart disease
despite maximal therapy, all of whom underwent transplantation of TCD-51073. No serious …
[PDF][PDF] Safety and Efficacy of Autologous Skeletal Myoblast Sheets (TCD-5 1073) for the Treatment of Severe Chronic Heart
K Kinugawa, S Miyagawa - Eur Heart J, 2011 - mhlw-grants.niph.go.jp
Background: Poor survival outcomes for patients with severe heart failure (HF) and the
donor shortage for heart transplantation warrant the development of myocardial
regenerative therapy. We performed a multicenter, phase li study to evaluate the safety and
efficacy of autologous skeletal myoblast sheets (TCD-51073). Methods and Results: In 3
study sites, we enrolled 7 patients with severe chronic HF due to ischemic heart disease
despite maximal therapy, all of whom underwent transplantation of TCD-51073. No serious …
donor shortage for heart transplantation warrant the development of myocardial
regenerative therapy. We performed a multicenter, phase li study to evaluate the safety and
efficacy of autologous skeletal myoblast sheets (TCD-51073). Methods and Results: In 3
study sites, we enrolled 7 patients with severe chronic HF due to ischemic heart disease
despite maximal therapy, all of whom underwent transplantation of TCD-51073. No serious …
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