… of the safety of nisin (E 234) in the light of new toxicological data … Nisin (E 234) is currently
an authorised food additive in the EU … (EC) 1333/2008 for use in several food categories. The …

… that the safety of nisin used as a food additive needs to be re-… As mentioned in the introduction,
nisin (E 234) is a lantibiotic (… of nisin delivered with all food products was below the toxic …

… on the safety in use of natamycin (E 235) as a food additive, … 4) was isolated as a light yellow
amorphous substance in a rather … purity of food additives and their toxicological evaluations: …

… safe’ (GRAS status; 53 FR 11247), and the European Union approved the usage of nisin as
a food additive—E234 … equipped with an artificial light program (fluorescent lights), automatic …

… as a food preservative, excellent safety record—and its designation as a natural food additive.
… significant toxic finding, and it was concluded that nisin was a safe substance for use in …

… 95/2/EC on food additives other than colours and sweeteners… about safety for introduction
into Japanese the market. … Treatment diets were put in plastic boxes, shielded from the light …

… of the food additive, respectively, these safety factors reflect the … are insoluble in water,
sensitive to light, pH, oxygen, and heat… Although there are currently no reports of nisin toxicity, it is …

… as a food preservative there were attempts to use nisin as a medical drug, but these
attempts failed due to nisin’s … It was concluded that the safety of cream, for instance in “ready-to-eat” …

… preservatives, nisin remains the only bacteriocin legally approved by regulatory agencies
as a food preservative. Moreover, insufficient data on the safety and toxicity of bacteriocins …

… effects, including toxicity, allergenic, alteration of food sensory properties, … preservative is
needed to maintain food quality without posing any health and other concerns related to food …