[HTML][HTML] Salmonella enterica Typhimurium SipA induces CXC-chemokine expression through p38MAPK and JUN pathways
The role of Salmonella typhimurium type III secretion system (T3SS-1)-translocated proteins
in chemokines' expression and protein phosphorylation was investigated in HeLa cells.
Infection of HeLa cells with S. typhimurium activated IL-8 and GRO-α expression at higher
levels than infection with a S. typhimurium sipAsopABDE2 mutant, confirming that T3SS-1-
secreted proteins are required to fully induce chemokine expression in HeLa cells. A S.
typhimurium sipAsopABDE2 mutant complemented with sipA or a strain carrying a …
in chemokines' expression and protein phosphorylation was investigated in HeLa cells.
Infection of HeLa cells with S. typhimurium activated IL-8 and GRO-α expression at higher
levels than infection with a S. typhimurium sipAsopABDE2 mutant, confirming that T3SS-1-
secreted proteins are required to fully induce chemokine expression in HeLa cells. A S.
typhimurium sipAsopABDE2 mutant complemented with sipA or a strain carrying a …
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