Salvianolic acid B alters the gut microbiota and mitigates colitis severity and associated inflammation

X Wu, L Wang, L Tang, L Wang, S Cao, Q Wu… - Journal of Functional …, 2018 - Elsevier
Consumption of Salvia miltiorrhiza could improve dextran sulfate sodium (DSS) induced
colitis. Whether salvianolic acid B (Sal B) can ameliorate colitis is still unclear. Here, colitis
induced by 2.2% DSS was treated with 100 mg/kg Sal B by oral gavage. Sal B improved
weight loss, disease activity index, mucosal damage and inflammatory cell infiltration in
colitis mice. Sal B could increase the production of acetic acid, propionic acid and valeric
acid in colitis mice. The reduction of diversity and richness of gut microbiota in colitis mice …

Salvianolic acid B alters the gut microbiota and mitigates colitis severity and associated inflammation.

WXY Wu XinYue, WLJ Wang LiJuan, TL Tang Lei… - 2018 - cabidigitallibrary.org
Consumption of Salvia miltiorrhiza could improve dextran sulfate sodium (DSS) induced
colitis. Whether salvianolic acid B (Sal B) can ameliorate colitis is still unclear. Here, colitis
induced by 2.2% DSS was treated with 100 mg/kg Sal B by oral gavage. Sal B improved
weight loss, disease activity index, mucosal damage and inflammatory cell infiltration in
colitis mice. Sal B could increase the production of acetic acid, propionic acid and valeric
acid in colitis mice. The reduction of diversity and richness of gut microbiota in colitis mice …
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