The article establishes a causal relationship between economic security and efficiency of the enterprise and hypothesizes about the need to expand approaches to analytical evaluation of efficiency, taking into account the security priorities of the enterprise. It has been proved that in the present conditions, the effectiveness of the activities of domestic enterprises is characterized not only by achieving a positive value of the financial result (profit), but also by the ability to withstand modern economic challenges to ensure the continuity of statutory activities. Therefore, the purpose of the article was to develop a safe-oriented model for evaluating the effectiveness of the enterprise and forming scientifically based recommendations for use as its methodological basis indicators that characterize the level of economic security. The methodological basis of the safety-oriented model is a system of balanced economic indicators, which ensures the evaluation of the efficiency of the enterprise from the standpoint of systemic integrity and enables multi-vector analysis of efficiency with trend determination and highlighting the most significant factors that influence the change in profitof the enterprise.. Unlike the classic efficiency assessment model based on coefficient analysis, which provides for the calculation of generalizing efficiency coefficients without taking into account external factors of influence on the activities of the enterprise, the safe and indicative model is based on methodological approaches to the consistency of certain groups of financial and economic indicators that characterize the impact of threats to the internal and external environment of the enterprise’s functioning to change the basic level of efficiency. The safety-oriented model of performance assessment was tested in the activities of agro-industrial enterprises. 2) in the emergence of reserves for increasing efficiency by leveling the impact of threats to the internal and externalenvironment; 3) establishing subordination between indicators in determining the general (effective) indicators that characterize the achieved level of efficiency of the enterprise; 4) the implementation of dynamic and factor analysis of the efficiency of the enterprise.