[HTML][HTML] Selective recruitment of nucleoporins on vaccinia virus factories and the role of Nup358 in viral infection
D Khuperkar, A Kamble, A Singh, A Ghate… - Virology, 2017 - Elsevier
Vaccinia virus (VACV), a member of the Poxviridae family, uses cytoplasmic factories for its
replication. Recent studies indicated that VACV infection requires a set of nucleoporins.
However, how the nucleoporins contribute to viral life cycle remains unclear. Here, we report
that the nucleoporins Nup62 and Nup358 localize to the cytoplasmic viral factories (VFs).
Nup358 was targeted to the VFs at 6 h post-infection (hpi), whereas Nup62, along with the
previously reported translation factors such as eIF4E, eIF3η and G3BP1, was recruited to the …
replication. Recent studies indicated that VACV infection requires a set of nucleoporins.
However, how the nucleoporins contribute to viral life cycle remains unclear. Here, we report
that the nucleoporins Nup62 and Nup358 localize to the cytoplasmic viral factories (VFs).
Nup358 was targeted to the VFs at 6 h post-infection (hpi), whereas Nup62, along with the
previously reported translation factors such as eIF4E, eIF3η and G3BP1, was recruited to the …
Selective recruitment of nucleoporins on vaccinia virus factories and the role of Nup358 in viral infection.
DK Deepak Khuperkar, AK Ashish Kamble… - 2017 - cabidigitallibrary.org
Vaccinia virus (VACV), a member of the Poxviridae family, uses cytoplasmic factories for its
replication. Recent studies indicated that VACV infection requires a set of nucleoporins.
However, how the nucleoporins contribute to viral life cycle remains unclear. Here, we report
that the nucleoporins Nup62 and Nup358 localize to the cytoplasmic viral factories (VFs).
Nup358 was targeted to the VFs at 6 h post-infection (hpi), whereas Nup62, along with the
previously reported translation factors such as eIF4E, eIF3η and G3BP1, was recruited to the …
replication. Recent studies indicated that VACV infection requires a set of nucleoporins.
However, how the nucleoporins contribute to viral life cycle remains unclear. Here, we report
that the nucleoporins Nup62 and Nup358 localize to the cytoplasmic viral factories (VFs).
Nup358 was targeted to the VFs at 6 h post-infection (hpi), whereas Nup62, along with the
previously reported translation factors such as eIF4E, eIF3η and G3BP1, was recruited to the …
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