[HTML][HTML] Selenium and tellurium in the development of novel small molecules and nanoparticles as cancer multidrug resistance reversal agents
E Domínguez-Álvarez, B Rácz, MA Marć… - Drug Resistance …, 2022 - Elsevier
Selenium is an essential trace element that is crucial for cellular antioxidant defense against
reactive oxygen species (ROS). Recently, many selenium-containing compounds have
exhibited a wide spectrum of biological activities that make them promising scaffolds in
Medicinal Chemistry, and, in particular, in the search for novel compounds with anticancer
activity. Similarly, certain tellurium-containing compounds have also exhibited substantial
biological activities. Here we provide an overview of the biological activities of seleno-and …
reactive oxygen species (ROS). Recently, many selenium-containing compounds have
exhibited a wide spectrum of biological activities that make them promising scaffolds in
Medicinal Chemistry, and, in particular, in the search for novel compounds with anticancer
activity. Similarly, certain tellurium-containing compounds have also exhibited substantial
biological activities. Here we provide an overview of the biological activities of seleno-and …
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