… Pancreas-mimicking glucose-responsive insulindelivery systems … hydrogel platform based on phenylboronic acid-functionalized natural silk fibroin protein for regulated insulindelivery. …
… as coupling agents, the hydrogel was synthesized for oral insulinadministration. Cell studies … As these peptidehydrogels effectively demonstrated control of blood glucose, they were …
… inventiveness of peptide-based hydrogels to treat diabetes and associated complications. … A closed-loop glucose-responsive insulindelivery system [49], using a pH-sensitive peptide …
… The glucose-sensitive hydrogels have attracted great attention in the field of insulin delivery to … a glucose-sensitive hydrogel for insulindelivery [12]. For example, glucose-responsive …
F Zhao, D Wu, D Yao, R Guo, W Wang, A Dong… - Acta biomaterialia, 2017 - Elsevier
… insulinhydrogel for glucose-regulated delivery of insulin based on a unique particle-hydrogel … hybrid system offers a promising strategy for long-acting and self-regulatedinsulindelivery …
SW Kim, CM Paii, M Kimiko, LA Seminoff… - Journal of controlled …, 1990 - Elsevier
… [ 11 ], with immobilized enzyme in a hydrogel where the gluconic acid protonates amine … It was demonstrated that the proposed concept for the delivery of insulin from a selfregulated …
R Ying, W Wang, R Chen, R Zhou, X Mao - Biomacromolecules, 2024 - ACS Publications
… -response polymer hydrogel using carboxymethyl agarose … ) was developed as an insulin delivery carrier, exhibiting excellent … insulindelivery methods, the hydrogel oral delivery system …
LR Volpatti, MA Matranga, AB Cortinas, D Delcassian… - ACS …, 2019 - ACS Publications
… -responsive insulindelivery in vivo, we coformulate rapid-release and prolonged-release acetalated dextran nanoparticles (Ac-dex NPs) encapsulating GOx, catalase, and insulin. We …
V Ravaine, C Ancla, B Catargi - Journal of Controlled Release, 2008 - Elsevier
… Instead of a hydrogel, a gating membrane can be used to deliverinsulin in a self-regulated fashion. … The ideal vector would enable insulindelivery in a self-regulated and long acting but …