[PDF][PDF] Sequence tube maps: making graph genomes intuitive to commuters
Bioinformatics, 2019•academic.oup.com
Motivation Compared to traditional haploid reference genomes, graph genomes are an
efficient and compact data structure for storing multiple genomic sequences, for storing
polymorphisms or for mapping sequencing reads with greater sensitivity. Further, graphs are
well-studied computer science objects that can be efficiently analyzed. However, their
adoption in genomic research is slow, in part because of the cognitive difficulty in
interpreting graphs. Results We present an intuitive graphical representation for graph …
efficient and compact data structure for storing multiple genomic sequences, for storing
polymorphisms or for mapping sequencing reads with greater sensitivity. Further, graphs are
well-studied computer science objects that can be efficiently analyzed. However, their
adoption in genomic research is slow, in part because of the cognitive difficulty in
interpreting graphs. Results We present an intuitive graphical representation for graph …
Motivation
Compared to traditional haploid reference genomes, graph genomes are an efficient and compact data structure for storing multiple genomic sequences, for storing polymorphisms or for mapping sequencing reads with greater sensitivity. Further, graphs are well-studied computer science objects that can be efficiently analyzed. However, their adoption in genomic research is slow, in part because of the cognitive difficulty in interpreting graphs.
Results
We present an intuitive graphical representation for graph genomes that re-uses well-honed techniques developed to display public transport networks, and demonstrate it as a web tool.
Availability and implementation
Code: https://github.com/vgteam/sequenceTubeMap.
Demonstration
https://vgteam.github.io/sequenceTubeMap/.
Supplementary information
Supplementary data are available at Bioinformatics online.
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