Sequencing and Genetic Variation of Multidrug Resistance Plasmids in Klebsiella pneumoniae
F Zhao, J Bai, J Wu, J Liu, M Zhou, S Xia, S Wang… - Plos one, 2010 - journals.plos.org
Background The development of multidrug resistance is a major problem in the treatment of
pathogenic microorganisms by distinct antimicrobial agents. Characterizing the genetic
variation among plasmids from different bacterial species or strains is a key step towards
understanding the mechanism of virulence and their evolution. Results We applied a deep
sequencing approach to 206 clinical strains of Klebsiella pneumoniae collected from 2002
to 2008 to understand the genetic variation of multidrug resistance plasmids, and to reveal …
pathogenic microorganisms by distinct antimicrobial agents. Characterizing the genetic
variation among plasmids from different bacterial species or strains is a key step towards
understanding the mechanism of virulence and their evolution. Results We applied a deep
sequencing approach to 206 clinical strains of Klebsiella pneumoniae collected from 2002
to 2008 to understand the genetic variation of multidrug resistance plasmids, and to reveal …
Sequencing and genetic variation of multidrug resistance plasmids in Klebsiella pneumoniae.
ZFQ Zhao FangQing, BJ Bai Jie, WJY Wu JinYu… - 2010 - cabidigitallibrary.org
Background: The development of multidrug resistance is a major problem in the treatment of
pathogenic microorganisms by distinct antimicrobial agents. Characterizing the genetic
variation among plasmids from different bacterial species or strains is a key step towards
understanding the mechanism of virulence and their evolution. Results: We applied a deep
sequencing approach to 206 clinical strains of Klebsiella pneumoniae collected from 2002
to 2008 to understand the genetic variation of multidrug resistance plasmids, and to reveal …
pathogenic microorganisms by distinct antimicrobial agents. Characterizing the genetic
variation among plasmids from different bacterial species or strains is a key step towards
understanding the mechanism of virulence and their evolution. Results: We applied a deep
sequencing approach to 206 clinical strains of Klebsiella pneumoniae collected from 2002
to 2008 to understand the genetic variation of multidrug resistance plasmids, and to reveal …
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