[HTML][HTML] Seroprevalence of SARS-CoV-2 significantly varies with age: Preliminary results from a mass population screening

G Pagani, F Conti, A Giacomelli… - The Journal of …, 2020 - ncbi.nlm.nih.gov
G Pagani, F Conti, A Giacomelli, D Bernacchia, R Rondanin, A Prina, V Scolari, CE Gandolfi…
The Journal of Infection, 2020ncbi.nlm.nih.gov
We read with interest the article by C. Dimeglio and colleagues, in which the authors apply a
mathematical model to conclude that a SARS-CoV-2 (Severe Acute Respiratory Sindrome
Coronavirus 2) seroprevalence of at least 50% is required to avoid an infection rebound
after removal of containment measures1. In our study we found that SARS-CoV-2
seroprevalence was dramatically lower than this threshold, even in an area of initially
unrestricted viral circulation. Italy was the first European country that suffered a wide spread …
We read with interest the article by C. Dimeglio and colleagues, in which the authors apply a mathematical model to conclude that a SARS-CoV-2 (Severe Acute Respiratory Sindrome Coronavirus 2) seroprevalence of at least 50% is required to avoid an infection rebound after removal of containment measures1. In our study we found that SARS-CoV-2 seroprevalence was dramatically lower than this threshold, even in an area of initially unrestricted viral circulation.
Italy was the first European country that suffered a wide spread of Coronavirus Disease 2019 (COVID-19), caused by a novel betacoronavirus which was first identified in China and denominated SARS-CoV-2 (Severe Acute Respiratory Sindrome Coronavirus 2), which caused hundreds of thousands of cases2. During the epidemic, testing was restricted to severely symptomatic cases. Consequently, the true extent of the SARS-CoV-2 infection remains unknown.
ncbi.nlm.nih.gov
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