Serotonin syndrome is a toxic condition due to serotoninergic hyperstimulation, which is
caused mostly by serotonergic agents either in overdose or in combination. The diagnosis is
purely clinical and poorly validated. We described a patient with tremor, mydriatic pupils,
clonus, and ataxia after a single dose of duloxetine; on the dosage of admission. Duloxetine
belongs to a large class of antidepressants called reuptake inhibitors. The case is presented
to emphasize this possible toxicity due to increasing availability of serotonergic agents. It is a …