[PDF][PDF] Serum level of interleukin-17 in patients with psoriasis

M Sobhan, HR Ghasemi Basir… - Immunopathol …, 2022 - immunopathol.com
Immunopathol Persa, 2022immunopathol.com
… Recent studies showed that interleukin-17 (IL-17) may play a role in the development of
psoriasis. Objectives: In this study, serum levels of IL-17 in psoriatic patients was compared with
healthy controls; besides, in patients with psoriasis, serum levels of IL-17 were compared with
pre-treatment levels, after topical treatments. Patients and Methods: In this case-control study,
serum levels of IL-17 were measured and compared in 30 psoriatic patients and 30 healthy
individuals matched to age, gender and body mass index. After evaluating the severity of …
Conclusion: In psoriatic patients, serum levels of IL-17 increased significantly compared to healthy subjects. Treatment of psoriasis with topical corticosteroids for four weeks reduced the serum level of IL-17 and the severity of disease.
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