Objective To study baseline serum neurofilament light chain (sNfL) levels as a prognostic
biomarker in Guillain-Barré syndrome (GBS). Methods We measured NfL in serum (98
samples) and cerebrospinal fluid (CSF)(24 samples) of patients with GBS prospectively
included in the International GBS Outcome Study (IGOS) in Spain using single-molecule
array (SiMoA) and compared them with 53 healthy controls (HCs). We performed
multivariable regression to analyse the association between sNfL levels and functional …

Objective: To study baseline serum neurofilament light chain (sNfL) levels as a prognostic
biomarker in Guillain-Barré syndrome (GBS). Methods: We measured NfL using SiMoA in
serum (98 samples) and CSF (24 samples) of GBS patients prospectively included in the
International GBS Outcome Study (IGOS) in Spain and compared them with controls (HC).
We performed multivariable regression to analyze the association between sNfL levels and
functional outcome at one year. Results: GBS patients had higher NfL levels than HC in …