Severe acute respiratory syndrome coronavirus 2 seroassay performance and optimization in a population with high background reactivity in Mali
J Woodford, I Sagara, A Dicko… - The Journal of …, 2021 - academic.oup.com
Background False positivity may hinder the utility of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) serological tests in sub-Saharan Africa. Methods From 312
Malian samples collected before 2020, we measured antibodies to the commonly tested
SARS-CoV-2 antigens and 4 other betacoronaviruses by enzyme-linked immunosorbent
assay (ELISA). In a subset of samples, we assessed antibodies to a panel of Plasmodium
falciparum antigens by suspension bead array and functional antiviral activity by SARS-CoV …
coronavirus 2 (SARS-CoV-2) serological tests in sub-Saharan Africa. Methods From 312
Malian samples collected before 2020, we measured antibodies to the commonly tested
SARS-CoV-2 antigens and 4 other betacoronaviruses by enzyme-linked immunosorbent
assay (ELISA). In a subset of samples, we assessed antibodies to a panel of Plasmodium
falciparum antigens by suspension bead array and functional antiviral activity by SARS-CoV …
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