purpose of this investigation was to elucidate the mechanisms through which high pressure
may elicit vascular dysfunction and determine the mechanisms through which regular
aerobic exercise protects arteries against high pressure. Male C57BL/6J mice were
subjected to 2 wk of voluntary running (~ 6 km/day) for comparison with sedentary controls.
Hindlimb adipose resistance arteries were dissected from mice for measurements of flow …