Short-term regular aerobic exercise reduces oxidative stress produced by acute high intraluminal pressure in the adipose microvasculature

AT Robinson, IS Fancher, V Sudhahar… - American Journal …, 2017 - journals.physiology.org
High blood pressure has been shown to elicit impaired dilation in the vasculature. The
purpose of this investigation was to elucidate the mechanisms through which high pressure
may elicit vascular dysfunction and determine the mechanisms through which regular
aerobic exercise protects arteries against high pressure. Male C57BL/6J mice were
subjected to 2 wk of voluntary running (~ 6 km/day) for comparison with sedentary controls.
Hindlimb adipose resistance arteries were dissected from mice for measurements of flow …

Short-term Regular Aerobic Exercise Reduces Oxidative Stress Produced by Acute High Intraluminal Pressure in the Adipose Microvasculature 2

T Fukai, SA Phillips - 2017 - journals.physiology.org
Purpose: High blood pressure has been shown to elicit impaired dilation in the vasculature.
The 36 purpose of this investigation was to elucidate the mechanisms through which high
pressure may 37 elicit vascular dysfunction, and determine the mechanisms through which
regular aerobic 38 exercise protects arteries against high pressure. Methods: Male C57Bl6
mice were subjected to 39 two weeks of voluntary running (~ 6km/day) for comparison to
sedentary controls. Hind limb 40 adipose resistance arteries were dissected from mice for …
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