Brain injury in children with sickle cell disease: prevalence and etiology

RG Steen, X Xiong, JW Langston… - Annals of Neurology …, 2003 - Wiley Online Library
… the relationship between brain injury by magnetic resonance … SS, the most serious form of
sickle cell disease. We reviewed … Large arteries were affected in 31% of brain injury patients, …

[HTML][HTML] Sickle Injury to Brain

M Ali, A Kumar, OM Hingora, F Ahmad - Open Journal of Modern …, 2014 - scirp.org
We reported a case of a 12-year-old girl child with an uncommon intracranial metallic foreign
body who was hit by her younger sister with sickle that got stuck to skull. Patient presented …

Silent cerebral infarcts: a review on a prevalent and progressive cause of neurologic injury in sickle cell anemia

MR DeBaun, FD Armstrong… - Blood, The Journal …, 2012 - ashpublications.org
… complications of sickle cell anemia (SCA) is cerebral injury, … The most common neurologic
injury in SCA is silent cerebral … brain magnetic resonance imaging in children with sickle cell …

Brain imaging findings in pediatric patients with sickle cell disease

RG Steen, T Emudianughe, GM Hankins, LW Wynn… - Radiology, 2003 - pubs.rsna.org
… If vascular injury is primary to brain injury, a patient with a vascular abnormality would be
expected to have a parenchymal abnormality, whereas a patient with normal vasculature would …

The spectrum of brain MR abnormalities in sickle-cell disease: a report from the Cooperative Study of Sickle Cell Disease.

FG Moser, ST Miller, JA Bello… - American Journal …, 1996 - Am Soc Neuroradiology
… The brains of young children with Hb SS are particularly vulnerable to ischemic injury (14). …
been implicated in the pathogenesis of brain injury in this patient population (5, 15– 18). …

Brain injury pathophysiology study by a multimodal approach in children with sickle cell anemia with no intra or extra cranial arteriopathy

V Brousse, C Pondarre, M Kossorotoff… - …, 2021 - pmc.ncbi.nlm.nih.gov
Brain injury is a major complication in sickle cell anemia (… in the border zone areas of the
brain, mainly in the deep white … Conventional MRI shows brain injury in a pattern suggestive of …

Brain infarction in sickle cell anemia: magnetic resonance imaging correlates

SG Pavlakis, J Bello, I Prohovnik… - Annals of Neurology …, 1988 - Wiley Online Library
… , and to accentuate the regional vulnerability of brain tissue in the watershed territories. These
two … Eleven percent of our nonstroke patients showed unexpected areas of cerebral injury. …

Cerebral oxygen metabolic stress, microstructural injury, and infarction in adults with sickle cell disease

Y Wang, S Fellah, ME Fields, KP Guilliams… - Neurology, 2021 - AAN Enterprises
… imaging studies with cognitive assessment will help to determine whether cerebral oxygen
metabolic stress temporally predicts microstructural and structural ischemic brain injury, as …

MRI detection of brain abnormality in sickle cell disease

H Stotesbury, JM Kawadler, DE Saunders… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Over the past decades, neuroimaging studies have clarified that a significant
proportion of patients with sickle cell disease (SCD) have functionally significant brain

Brain Age Modeling and Cognitive Outcomes in Young Adults With and Without Sickle Cell Anemia

AL Ford, S Fellah, Y Wang, K Unger-Levinson… - JAMA Network …, 2025 - jamanetwork.com
… associated with BAG and the ability of BAG to estimate cognitive performance compared
to neuroimaging metrics of brain health and ischemic brain injury, such as normalized whole …