This study presents the sintering of new forsterite ceramics (FCs) using nano forsterite powder, obtained by a sol-gel method. The forsterite ceramics were sintered between 1200 and 1450 C. The resulted forsterite ceramics, namely FC at sintering temperature, T, written as FC (T), were characterized by various methods, XRD, AFM, apparent density, porosity and shrinkage. Mechanical properties were determined for FC (1400), with a Young elastic modulus at about 43.84 GPa and nano-indentation hardness at around 3.07 GPa. Furthermore, the in vitro biocompatibility of FC (1200) was evaluated using cell staining with fluorescein diacetate, FDA, assay. The cell viability results confirmed that forsterite ceramic, FC (1200), promotes cell adhesion and proliferation in cell culture, with no significant cytotoxic effects. These findings strongly recommend the new forsterite ceramics, as potential biomaterials for biomedical applications.