Here we review the current knowledge about the mutations of the gene encoding the
cardiac ryanodine receptor (RyR2) that cause cardiac arrhythmias. Similarities between the …

… Ca 2+ release channel of the sarcoplasmic reticulum (SR), resulting in opening of the channel
and release of Ca 2+ … ryanodine receptors is the opening of the channel pore of the latter. …

… describes the existence of two pharmacologically distinct types of Ca2+ channels in rat
skeletal muscle cells (myoballs) in culture. The first class of Ca2+ channels is insensitive to the …

… of the open channel and applies to theCa channel of skeletal muscle in the same wayas
other estimates of pore size apply to other channels. Whether other Ca channels havea similarly …

… As well as the Ca 2+ channopathies in human skeletal muscle, this review will introduce
the role of intracellular Ca 2+ -release and extracellular Ca 2+ -entry in skeletal muscle …

… Ca 2+ release have been examined by incorporating the purified rabbit skeletal muscle Ca
2+ release channel … single channels showed that Ca 2÷- and ATP-gated channel activity was …

… (pO 2 ), whereas tissue pO 2 is much lower. The skeletal muscle calcium release channel/…
Here we report that pO 2 dynamically controls the redox state of 6–8 out of 50 thiols in each …

… The Ca2+-dependent kinetics of large-conductance Ca2+-activated K' channels from cultured
rat skeletal muscle … About 2 x 105 open and shut intervals were analysed from each of five …

… ,4,5-trisphosphate (IP 3 )-induced Ca 2+ release (254). … Ca 2+ release in cardiac muscle.
It is generally agreed that an influx of Ca 2+ through L-type voltage-dependent Ca 2+ channels …

… channels, is thought to underlie Ca 2+ sparks and the peak phase of release in frog skeletal
muscle. A … by CICR to Ca 2+ release triggered by depolarization, and a lack of concerted …