… implicated in disease, suggesting that modulation of phase transitions could be a possible
… phase behaviour of stress granule proteins in the cytoplasm could be a novel route to treat …

… modulation of phase behavior by small molecules and demonstrate that this modulatory
capacity extends to a number of proteins… of cells treated with bis-ANS revealed that the molecule …

… provide new strategies for disease treatment. There are several … vivo by modulating membrane
LLPS with extracellular DNA … In this study, the release rate of small molecule drugs can be …

… modulate biological condensates are summarized and discussed. Possible strategies to
accelerate the discovery of more liquid-liquid phase separation (LLPS)-regulating small … to treat …

… of SMMs on phase-separated droplets, tau–Zn LLPS was induced (10 min) and treated with
… The quantification of droplet size revealed the increased size in Zn treated samples to 2.26-…

… reduces hnRNPA2 phase separation and destabilizes the … of small ubiquitin-like modifiers
(SUMOs) that modulate cellular … protein being released and nuclear bodies being separated …

… field while also opening up new avenues for investigating disease pathology and treatment.
… driven by intrinsically disordered histone tails. LLPS of chromatin can be modulated by post-…

… a process known as liquid-liquid phase separation (LLPS) to … molecule drug treatment, RNA
interference, and DNA editing. … that small molecule drug treatment can effectively modulate …

… We highlight important findings regarding the mechanisms underlying LLPS-modulated …
receptors, could be selectively disrupted by the treatment of an anti-HIV drug elvitegravir (EVG). …

… is expanding, cancer treatment based on phase separation is just … small molecules be
designed to precisely regulate phase … microbiota through phase separation modulation could offer …