Introduction Glioblastoma efficient drug delivery is hurdled by several pathophysiological
barriers of the tumor microenvironment and the intrinsic limitations of chemotherapeutic
agents. To overcome these drawbacks, we developed smart chlorotoxin (CTX)-
functionalized liposomes (LS) for sunitinib (STB) targeted delivery into glioblastoma cells.
Methods The synthesized liposomes in terms of physicochemical parameters, drug
encapsulation efficiency (EE%) and release profile, cytotoxicity, targeted cellular uptake by …