Solubility of acetaminophen and ibuprofen in binary and ternary mixtures of polyethylene glycol 600, ethanol and water

S Soltanpour, A Jouyban - Chemical and Pharmaceutical Bulletin, 2010 - jstage.jst.go.jp
Experimental solubilities of acetaminophen and ibuprofen in polyethylene glycol 600–water,
ethanol–polyethylene glycol 600, and polyethylene glycol 600–water–ethanol mixtures at 25
C are reported. The solubilities of drugs in the presence of ethanol and polyethylene glycol
600 were increased. The Jouyban–Acree model was used to fit the solubility data of each
drug in the binary mixtures in which the overall mean relative deviations (OMRDs) for
acetaminophen and ibuprofen were 2.9% and 4.3%, respectively. The OMRDs for ternary …

Solubility of acetaminophen and ibuprofen in binary and ternary mixtures of polyethylene glycols 200 and 400, propylene glycol, and water at 25 C

S Soltanpour, A Jouyban - Chemical Engineering Communications, 2014 - Taylor & Francis
The solubilities of acetaminophen and ibuprofen in the mixtures of propylene glycol-water,
polyethylene glycols 200-and 400-propylene glycol, and polyethylene glycols 200-and 400-
propylene glycol-water (122 data points) at 25° C were determined and mathematically
represented by the Jouyban-Acree model. The solubilities were measured using the shake
flask method, and the model was used to fit the solubility data of each drug in the solvent
mixtures. The density of the solute-free solvent mixtures was measured and the density of …
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