St. John's wort (Hypericum perforatum L.) and kindling epilepsy in rabbit
V Ivetic, M Popovic, N Mimica-Dukic, O Barak, V Pilija - Phytomedicine, 2002 - Elsevier
Effects of different extracts of Hypericum perforatum L. on the kindling epileptic discharges
were analyzed. The experiment was carried out on Chinchilla rabbits with chronically
implanted electrodes in cortical structures and hippocampus. In our study we used water, n-
butanol and ether fractions (mass concentrations 0.1 g/ml) of crude ethanol extract of
Hypericum perforatum. The particular extracts were given intramuscularly in single dose of 1
ml/kg BW. The bioelectric activity was registered before and after applications of each …
were analyzed. The experiment was carried out on Chinchilla rabbits with chronically
implanted electrodes in cortical structures and hippocampus. In our study we used water, n-
butanol and ether fractions (mass concentrations 0.1 g/ml) of crude ethanol extract of
Hypericum perforatum. The particular extracts were given intramuscularly in single dose of 1
ml/kg BW. The bioelectric activity was registered before and after applications of each …
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