Static and dynamic characteristics of cerebral blood flow during the resting state

Q Zou, CW Wu, EA Stein, Y Zang, Y Yang - Neuroimage, 2009 - Elsevier
In this study, the static and dynamic characteristics of cerebral blood flow (CBF) in the resting
state were investigated using an arterial spin labeling (ASL) perfusion imaging technique.
Consistent with previous PET results, static CBF measured by ASL was significantly higher
in the posterior cingulate cortex (PCC), thalamus, insula/superior temporal gyrus (STG) and
medial prefrontal cortex (MPFC) than the average CBF of the brain. The dynamic
measurement of CBF fluctuations showed high correlation (functional connectivity) between …

Static and dynamic characteristics of cerebral blood flow during the resting state in schizophrenia

J Kindler, K Jann, P Homan, M Hauf… - Schizophrenia …, 2015 - academic.oup.com
Background: The cerebral network that is active during rest and is deactivated during goal-
oriented activity is called the default mode network (DMN). It appears to be involved in self-
referential mental activity. Atypical functional connectivity in the DMN has been observed in
schizophrenia. One hypothesis suggests that pathologically increased DMN connectivity in
schizophrenia is linked with a main symptom of psychosis, namely, misattribution of
thoughts. Methods: A resting-state pseudocontinuous arterial spin labeling (ASL) study was …
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