Statin use and the risk of incident dementia: the Cardiovascular Health Study
Background Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) reduce
cardiovascular risk through mechanisms that might affect the development of dementia.
Objective To evaluate whether statin use is associated with a lower risk of dementia
compared with never use of lipid-lowering agents (LLAs). Design Cohort study of community-
dwelling adults 65 years and older. The analysis included 2798 participants free of dementia
at baseline. Main Outcome Measures Using Cox proportional hazards regression analysis …
cardiovascular risk through mechanisms that might affect the development of dementia.
Objective To evaluate whether statin use is associated with a lower risk of dementia
compared with never use of lipid-lowering agents (LLAs). Design Cohort study of community-
dwelling adults 65 years and older. The analysis included 2798 participants free of dementia
at baseline. Main Outcome Measures Using Cox proportional hazards regression analysis …
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