Statistical analysis and exposure status classification of transmembrane beta barrel residues
Several computational methods exist for the identification of transmembrane beta barrel
proteins (TMBs) from sequence. Some of these methods also provide the transmembrane
(TM) boundaries of the putative TMBs. The aim of this study is to (1) derive the propensities
of the TM residues to be exposed to the lipid bilayer and (2) to predict the exposure status (ie
exposed to the bilayer or hidden in protein structure) of TMB residues. Three novel
propensity scales namely, BTMC, BTMI and HTMI were derived for the TMB residues at the …
proteins (TMBs) from sequence. Some of these methods also provide the transmembrane
(TM) boundaries of the putative TMBs. The aim of this study is to (1) derive the propensities
of the TM residues to be exposed to the lipid bilayer and (2) to predict the exposure status (ie
exposed to the bilayer or hidden in protein structure) of TMB residues. Three novel
propensity scales namely, BTMC, BTMI and HTMI were derived for the TMB residues at the …
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