Site-specific delivery of the therapeutic agents to the target site is the most challenging and
most important goal from the clinical point of view. Recently, much effort has been indulged
in developing targeted drug delivery systems, especially for tumor, instead of introducing
new drugs. Stimuli-nanocarriers are the significant results of these efforts. In this regard,
internal stimuli such as temperature, pH, hypoxia, redox potential as well as some external
stimuli like ultrasound, light, and magnetic field were exploited. The stimuli-responsive …