Stratified premedication strategy for the prevention of contrast media hypersensitivity in high-risk patients

SY Lee, MS Yang, YH Choi, CM Park, HW Park… - Annals of Allergy …, 2017 - Elsevier
Background Although the severity of hypersensitivity reactions to iodinated contrast media
varies, it is well correlated with the severity of recurrent reactions; however, prophylaxis
protocols are not severity-stratified. Objective To assess the outcomes of tailored prophylaxis
according to the severity of hypersensitivity reactions to iodinated contrast media. Methods
Our premedication protocols were stratified based on the severity of previous reactions:(1) 4
mg of chlorpheniramine for mild reactions,(2) adding 40 mg of methylprednisolone for …
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