Huntington's disease (HD) is a neurodegenerative disorder largely governed by genetics.
The cause of this tandem repeat disorder is a fully penetrant trinucleotide (CAG), inherited
via autosomal dominant transmission. The length of this expanded tandem repeat in HD
also predicts the age of disease onset, which can range from early childhood to late
adulthood. Previous research utilizing transgenic HD mice demonstrated that environmental
factors can alter symptom progression. Environmental enrichment and voluntary wheel …