Chitosan, a load-bearing biomacromolecule found in the exoskeletons of crustaceans and
insects, is a promising biopolymer for the replacement of synthetic plastic compounds. Here,
surface interactions mediated by chitosan in aqueous solutions, including the effects of pH
and contact time, were investigated using a surface forces apparatus (SFA). Chitosan films
showed an adhesion to mica for all tested pH ranges (3.0–8.5), achieving a maximum value
at pH 3.0 after a contact time of 1 h (W ad∼ 6.4 mJ/m2). We also found weak or no cohesion …

2O7-14 이정승(14: 10-14: 20) Biomimetic, Sticky Hyaluronic Acid Hydrogel for Hepatocyte
Transplantation 이정승, 신지수, 이기홍, 조승우† 연세대학교 Hepatocyte transplantation has
been considered as an alternative to orthotopic liver transplantation. However, it is critical to
improve hepatocyte engraftment to minimize the loss of transplanted cells. In this study, we
synthesized catechol-functionalized hyaluronic acid (HA-CA) conjugate to prepare a sticky
hydrogel for efficient hepatocyte transplantation. The viability of hepatocytes encapsulated in …