[HTML][HTML] Structural remodeling and conduction velocity dynamics in the human left atrium: relationship with reentrant mechanisms sustaining atrial fibrillation

S Honarbakhsh, RJ Schilling, M Orini, R Providencia… - Heart rhythm, 2019 - Elsevier
Background Rate-dependent conduction velocity (CV) slowing is associated with atrial
fibrillation (AF) initiation and reentrant mechanisms. Objective The purpose of this study was
to assess the relationship between bipolar voltage, CV dynamics, and AF drivers. Methods
Patients undergoing catheter ablation for persistent AF (< 24 months) were enrolled.
Unipolar electrograms were recorded with a 64-pole basket catheter during atrial pacing at 4
pacing intervals (PIs) during sinus rhythm. CVs were measured between pole pairs along …

P1151 Structural remodeling and conduction velocity dynamics in the human left atrium: relationship with reentrant mechanisms sustaining atrial tachycardia and atrial …

S Honarbakhsh, RJ Schilling, M Orini… - EP …, 2018 - academic.oup.com
Methods: Patients undergoing catheter ablation for persistent AF (< 24months) were
included. Unipolar signals were recorded with a 64-pole whole-chamber basket catheter
and the signals were analyzed by the CARTOFINDER mapping system to create dynamic
wavefront maps from which local drivers with rotational (≥ 1.5 rotations of 360 degrees) or
focal activity (focal with radial activation over≥ 2 consecutive wavefronts) in the left atrium
were identified. The effect of ablation on drivers identified post-PV isolation (PVI) was …
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