solved the structures of domains II and III, which stimulate arrested polymerase II elongation
complexes in order to resume transcription. Domain I is conserved in evolution from yeast to
human species and is homologous to the transcription factors elongin A and CRSP70.
Domain I also interacts with the transcriptionally active RNA polymerase II holoenzyme and
therefore, may have a function unrelated to the previously described transcription elongation …