Structures and anticancer activity of chlorido platinum (II) saccharinate complexes with mono-and dialkylphenylphosphines

C Icsel, VT Yilmaz, B Cevatemre, M Aygun… - Journal of Inorganic …, 2019 - Elsevier
Abstract cis-[PtCl (sac)(PPh 2 Me) 2](1), cis-[PtCl (sac)(PPhMe 2) 2](2), trans-[PtCl (sac)(PPh
2 Et) 2](3) and trans-[PtCl (sac)(PPhEt 2) 2](4) complexes (sac= saccharinate) were
synthesized and characterized by elemental analysis and spectroscopic methods. The
structures of 2–4 were determined by X-ray single-crystal diffraction. The interaction of the
complexes with DNA was studied various biochemical, biophysical and molecular docking
methods. Only the cis-configured complexes (1 and 2) showed nuclease activity and their …
被引用次数：25 相关文章 所有 8 个版本

Structures and anticancer activity of chlorido platinum (II) saccharinate complexes with mono-and dialkylphenylphosphines

B Cevatemre, M Aygun, E Ulukaya - 2019 - acikerisim.uludag.edu.tr
Cis-[PtCl (sac)(PPh2Me)(2)](1), cis-[PtCl (sac)(PPhMe2)(2)](2), trans-[PtCl
(sac)(PPh2Et)(2)](3) and trans-[PtCl (sac)(PPhEt2)(2)](4) complexes (sac= saccharinate)
were synthesized and characterized by elemental analysis and spectroscopic methods. The
structures of 2-4 were determined by X-ray single-crystal diffraction. The interaction of the
complexes with DNA was studied various biochemical, biophysical and molecular docking
methods. Only the cis-configured complexes (1 and 2) showed nuclease activity and their …
相关文章 所有 2 个版本
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