Studies on the molecular correlates of genomic stability in rat brain cells following Amalakirasayana therapy

U Swain, KK Sindhu, U Boda, S Pothani… - Mechanisms of ageing …, 2012 - Elsevier
Adult Wistar NIN (WNIN) rats (6 months old) of both sexes were orally fed Amalakirasayana
at a dose of 4.5 g per kg body weight, five days in a week. The Amalakirasayana was
prepared by Arya Vaidya Sala, Kottakkal, Kerala, India, which is considered as gold
standard. After 3, 9 and 15 months of such therapeutic regime, rats were sacrificed and
various tissues including brain were removed. Isolated cell suspensions of neurons and
astroglia were prepared from the cerebral cortex. DNA damage, as a prime indicator of the …

Studies on the molecular correlates of genomic stability in rat brain cells following Amalakirasayana therapy.

US Umakanta Swain, KK Sindhu, UB Ushasri Boda… - 2012 - cabidigitallibrary.org
Abstract Adult Wistar NIN (WNIN) rats (6 months old) of both sexes were orally fed
Amalakirasayana at a dose of 4.5 g per kg body weight, five days in a week. The
Amalakirasayana was prepared by Arya Vaidya Sala, Kottakkal, Kerala, India, which is
considered as gold standard. After 3, 9 and 15 months of such therapeutic regime, rats were
sacrificed and various tissues including brain were removed. Isolated cell suspensions of
neurons and astroglia were prepared from the cerebral cortex. DNA damage, as a prime …