[HTML][HTML] Study of bioaccumulation of dalteparin at a prophylactic dose in patients with various degrees of impaired renal function
P Schmid, D Brodmann, AG Fischer… - Journal of Thrombosis and …, 2009 - Elsevier
Background: Low-molecular-weight heparins (LMWH) have been shown to be effective and
safe for prophylaxis of thromboembolic diseases. However, issues regarding safety and
optimal use of LMWH arise in patients with renal insufficiency (RI). Objectives: To compare
pharmacokinetic data of dalteparin for up to 3 weeks in patients with various degrees of RI.
Patients and methods: Patients from general medical and surgical wards were included in
this prospective cohort study and divided into three groups according to renal function: A …
safe for prophylaxis of thromboembolic diseases. However, issues regarding safety and
optimal use of LMWH arise in patients with renal insufficiency (RI). Objectives: To compare
pharmacokinetic data of dalteparin for up to 3 weeks in patients with various degrees of RI.
Patients and methods: Patients from general medical and surgical wards were included in
this prospective cohort study and divided into three groups according to renal function: A …
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