The current study includes a comparison of a number of biochemical variables   and the percentage of fatty acids in the blood of patients with Laryngeal and pharyngeal cancer who were diagnosed with the disease, as (25) samples were chosen for patients in the Oncology and Atomic Medicine Hospital in the city of Mosul from various age groups, in addition to (25) samples of healthy people. They did not suffer from any disease and in the same age groups as a control group. Where a number of biochemical variables and the percentage of fatty acids were measured using different techniques and the results of this study showed the presence of many significant differences for the studied variables, which indicates the existence of a significant effect of the studied disease condition on these variables.