Studying tumor angiogenesis and cancer invasion in a threedimensional vascularized breast cancer micro‐environment

M Dey, B Ayan, M Yurieva, D Unutmaz… - Advanced …, 2021 - Wiley Online Library
… These interactions induce genetic and metabolic alterations creating a conducive environment
for tumor growth. In this study, a physiologically relevant 3D vascularized breast cancer

Tissue-engineered three-dimensional tumor models to study tumor angiogenesis

SS Verbridge, EM Chandler… - Tissue Engineering Part …, 2010 - liebertpub.com
… pro-angiogenic factors that drive tumor vascularization. Although … invasion angiogenesis and
blood vessel permeability. … in breast-cancer—recapitulation of tumor environment in culture …

[HTML][HTML] Engineering a vascularized 3D hybrid system to model tumor-stroma interactions in breast cancer

FC Teixeira, S Chaves, AL Torres… - … in bioengineering and …, 2021 - frontiersin.org
… In future studies, we intend to evaluate how vascular EC … a hybrid 3D tumor angiogenesis
model, with both vascularized stromal … The use of 3D tumor angiogenesis models to study the …

[HTML][HTML] Three-dimensional models to study breast cancer

M Huerta-Reyes… - … Journal of Oncology, 2021 - spandidos-publications.com
… , along with the study of ECM components during tumor metastasis, invasion or angiogenesis.
… For example, in spheroid models, the lack of vascularization limits their use as a model of …

Microfluidic tumor–vascular model to study breast cancer cell invasion and intravasation

S Nagaraju, D Truong, G Mouneimne… - Advanced healthcare …, 2018 - Wiley Online Library
cancer cells were incorporated into the models to create 3D vascularized tumor models to
study involvement of tumor… [6] The overall goal of this study was to construct angiogenesis and …

[HTML][HTML] Breast cancer cell invasion into a three dimensional tumor-stroma microenvironment

D Truong, J Puleo, A Llave, G Mouneimne, RD Kamm… - Scientific reports, 2016 - nature.com
… In this study, to model 3D chemotactic tumor-stroma invasion in vitro, we developed an
innovative … cells in vivo have been shown to migrate toward one specific areas of vascularization. …

Evaluation of Three-Dimensional in Vitro Models to Study Tumor Angiogenesis

LJ Bray, C Werner - ACS Biomaterials Science & Engineering, 2018 - ACS Publications
… of vascularized cancer tissue for research purposes. … factors in tumor angiogenesis and
breast cancer morphogenesis. … toward the ovarian cancer cells, eventually invading them. These …

In vitro vascularized tumor platform for modeling tumor‐vasculature interactions of inflammatory breast cancer

M Gadde, C Phillips, N Ghousifam… - Biotechnology and …, 2020 - Wiley Online Library
… in vitro vascularized platforms introduced in this study model … two dimensional (2D) monolayers,
and three dimensional (3D) … further studies to confirm whether the vascular angiogenesis

Tissue-engineered 3D tumor angiogenesis models: potential technologies for anti-cancer drug discovery

K Chwalek, LJ Bray, C Werner - Advanced drug delivery reviews, 2014 - Elsevier
… of breast cancer cells and their pro-angiogenic invasive … cells support EC invasion during
angiogenesis by expression of … tools to study cancer vascularization using pathologically …

Multiscale and multi-modality visualization of angiogenesis in a human breast cancer model

J Cebulla, E Kim, K Rhie, J Zhang, AP Pathak - Angiogenesis, 2014 - Springer
… has revealed different aspects of tumor angiogenesis [5]. For … Therefore, the goal of this study
was to develop and validate … in tumor vascularity between viable and necrotic tumor tissue …