Sub-growth Inhibitory Concentrations of Some Antibiotics Enhance Serum Susceptibility of Escherichia Coli at Elevated Temperature
YB Ngwai - Asian Journal of Pharmaceutical and Health Sciences, 2011 - ajphs.com
The ability of antibiotics to interact with host defenses provide justification for in vitro
evaluation of the interaction of antibiotics, bacteria, and host defenses to help identify those
factors that influence therapy for bacterial infections. This study evaluates the effect of sub-
inhibitory concentrations (sub-MICs) of ceftriaxone, ciprofloxacin and gentamicin on killing of
Escherichia coli ATCC 25922 by human serum. Saline-washed 18-h Mueller-Hinton broth
culture of test strain was inoculated into 50% human serum-Hanks’ Balanced Salt …
evaluation of the interaction of antibiotics, bacteria, and host defenses to help identify those
factors that influence therapy for bacterial infections. This study evaluates the effect of sub-
inhibitory concentrations (sub-MICs) of ceftriaxone, ciprofloxacin and gentamicin on killing of
Escherichia coli ATCC 25922 by human serum. Saline-washed 18-h Mueller-Hinton broth
culture of test strain was inoculated into 50% human serum-Hanks’ Balanced Salt …