This paper demonstrates preliminary in-human validity of a novel subject-specific approach
to estimation of central aortic blood pressure (CABP) from peripheral circulatory waveforms.
In this “Individualized Transfer Function”(ITF) approach, CABP is estimated in two steps.
First, the circulatory dynamics of the cardiovascular system are determined via model-based
system identification, in which an arterial tree model is characterized based on the
circulatory waveform signals measured at the body's extremity locations. Second, CABP …

This paper demonstrates in-human validity of a novel subject-specific approach to
estimation of central aortic blood pressure from peripheral circulatory signals. In this
“Individualized Transfer Function”(ITF) approach, the unknown circulatory dynamics of
cardiovascular system are determined via system identification by characterizing its parallel
tube-load model representation based on circulatory signals measured at upper and lower
extremity locations. Then a stable input de-convolution algorithm is used to estimate central …