mepivacaine with epinephrine in inferior alveolar nerve block. A double-blind, randomized,
placebo-controlled, crossover clinical trial was conducted. Twenty healthy young volunteers
were randomized into two treatment sequences using a series of random numbers.
Sequence 1: Group A, 2% mepivacaine with 1: 100,000 epinephrine plus submucous
tramadol 50mg (1mL of saline) and one week later Group B, 2% mepivacaine with 1 …