Suboptimal bonding impairs hormonal, epigenetic and neuronal development in preterm infants, but these impairments can be reversed

D Kommers, G Oei, W Chen, L Feijs… - Acta …, 2016 - Wiley Online Library
D Kommers, G Oei, W Chen, L Feijs, S Bambang Oetomo
Acta Paediatrica, 2016Wiley Online Library
This review aimed to raise awareness of the consequences of suboptimal bonding caused
by prematurity. In addition to hypoxia–ischaemia, infection and malnutrition, suboptimal
bonding is one of the many unnatural stimuli that preterm infants are exposed to,
compromising their physiological development. However, the physiological consequences
of suboptimal bonding are less frequently addressed in the literature than those of other
threatening unnatural stimuli. Conclusion This review found that suboptimal bonding …
Abstract
This review aimed to raise awareness of the consequences of suboptimal bonding caused by prematurity. In addition to hypoxia–ischaemia, infection and malnutrition, suboptimal bonding is one of the many unnatural stimuli that preterm infants are exposed to, compromising their physiological development. However, the physiological consequences of suboptimal bonding are less frequently addressed in the literature than those of other threatening unnatural stimuli.
Conclusion
This review found that suboptimal bonding significantly impaired hormonal, epigenetic and neuronal development, but these impairments could be reversed by bonding interventions. This suggests that neonatal intensive care units should focus more on interventions that optimise bonding.
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