Subtractive genome analysis for in silico identification and characterization of novel drug targets in Streptococcus pneumonia strain JJA
Streptococcus pneumoniae (pneumococcus) is a Gram-positive bacterium. Humans are the
major target for the pneumococcus. The pneumococcus is a common etiological agent of
many different diseases such as bacterial meningitis, pneumonia, otitis media (OM),
sinusitis, and conjunctivitis. According to the WHO, the pneumococcus is responsible for
causing 1 million deaths each year. In 2000, over 14 million children worldwide under the
age of 5 years were diagnosed with a pneumococcal disease, with the highest incidence …
major target for the pneumococcus. The pneumococcus is a common etiological agent of
many different diseases such as bacterial meningitis, pneumonia, otitis media (OM),
sinusitis, and conjunctivitis. According to the WHO, the pneumococcus is responsible for
causing 1 million deaths each year. In 2000, over 14 million children worldwide under the
age of 5 years were diagnosed with a pneumococcal disease, with the highest incidence …
[PDF][PDF] Subtractive genome analysis for in silico identification and characterization of novel drug targets in C. trachomatis STRAIN D/UW-3/Cx
K Shoukat, N Rasheed, M Sajid - Int. J. Curr. Res, 2012 - researchgate.net
Chlamydia trachomatis is globally accepted as the most common cause of bacterial sexually
transmitted infections (STIs) that leads to further complications such as Pelvic Inflammatory
Diseases (PIDs), ectopic pregnancies, cervicitis, chronic pelvic pain and infertility (Morre et
al., 2006). C. trachomatis, an obligate human pathogen includes three human biovars:
serovars A, B, Ba or C cause ocular blindness or trachoma whereas various strains of
serovar DK are associated with the urogenital infections. Lymphogranuloma venereum …
transmitted infections (STIs) that leads to further complications such as Pelvic Inflammatory
Diseases (PIDs), ectopic pregnancies, cervicitis, chronic pelvic pain and infertility (Morre et
al., 2006). C. trachomatis, an obligate human pathogen includes three human biovars:
serovars A, B, Ba or C cause ocular blindness or trachoma whereas various strains of
serovar DK are associated with the urogenital infections. Lymphogranuloma venereum …