Currently, chaos-based cryptosystems are being proposed in the literature to provide confidentiality for digital images, since the diffusion effect in the Advance Encryption Standard (AES) algorithm is weak. Security is the most important challenge to assess in cryptosystems according to the National Institute of Standard and Technology (NIST), then cost and performance, and finally algorithm and implementation. Recent chaos-based image encryption algorithms present basic security analysis, which could make them insecure for some applications. In this paper, we suggest an integral analysis framework related to comprehensive security analysis, cost and performance, and the algorithm and implementation for chaos-based image cryptosystems. The proposed guideline based on 20 analysis points can assist new cryptographic designers to present an integral analysis of new algorithms. Future comparisons of new schemes can be more consistent in terms of security and efficiency. In addition, we present aspects regarding digital chaos implementation, chaos validation, and key definition to improve the security of the overall cryptosystem. The suggested guideline does not guarantee security, and it does not intend to limit the liberty to implement new analysis. However, it provides for the first time in the literature a solid basis about integral analysis for chaos-based image cryptosystems as an effective approach to improve security.