Sun exposure and vitamin D are independent risk factors for CNS demyelination

…, A Coulthard, C Chapman, I van der Mei, D Williams… - Neurology, 2011 - AAN Enterprises
Sun exposure and vitamin D status may have independent roles in the risk of CNS
demyelination… cell–mediated autoimmune disease of the CNS, is uncertain. Positive latitude …

Vitamin D as a risk factor for multiple sclerosis: immunoregulatory or neuroprotective?

SE Gombash, PW Lee, E Sawdai… - Frontiers in …, 2022 - frontiersin.org
… inflammatory demyelinating disease of the central nervous system (CNS). Since vitamin
D was … A study in EAE found that UV light suppressed EAE independent of VitD and VDR (66). …

Association between sun exposure, vitamin D intake, serum vitamin D level, and immunoglobulin G level in patients with neuromyelitis optica spectrum disorder

V Shaygannejad, MB Maljaei, SS Bank… - … Journal of Preventive …, 2018 - journals.lww.com
… be independently associated with the CNS demyelination onset … Vitamin D status and low
past or current sun exposure are independent risk factors for the development of MS and CNS

Ultraviolet radiation, vitamin D and multiple sclerosis

RM Lucas, SN Byrne, J Correale… - Neurodegenerative …, 2015 - Taylor & Francis
… Thus UVR, concurrently or independently of vitamin D may … number of T Regs in the CNS of
UV-irradiated mice at the time … derived phagocytes initiate demyelination and oxidative stress …

Vitamin D supplementation in central nervous system demyelinating disease—enough is enough

D Häusler, MS Weber - International Journal of Molecular Sciences, 2019 - mdpi.com
… of a potential MS risk factor by vitamin D supplementation has gained much … sun exposure,
which appears to mediate beneficial effects independent or in addition to raising the vitamin D

Interdependence and contributions of sun exposure and vitamin D to MRI measures in multiple sclerosis

R Zivadinov, CN Treu, B Weinstock-Guttman… - Journal of Neurology …, 2013 - jnnp.bmj.com
Sun exposure and vitamin D were reported to be independent risk factors for CNS demyelination
in … Greater UV induced skin damage and higher vitamin D levels were associated with a …

Vitamin D status and its contribution to multiple sclerosis risk: Insights gained through the study of children with central nervous system demyelination

H Hanwell - 2012 - library-archives.canada.ca
… Finally, a sun exposure questionnaire was validated in the … thesis focuses on vitamin D, other
candidate risk factors for MS, … UVR suppressed EAE independent of vitamin D3 production; …

Environmental risk factors for multiple sclerosis. Results from animal and human studies on diet, vitamin D and Epstein-Barr virus

Ø Torkildsen - 2010 - bora.uib.no
… changes in the cuprizone model for demyelination (article II) … This study demonstrated that
childhood sun exposure … induces an inflammatory demyelination in the CNS of the animal. In …

Vitamin D metabolites and risk of first clinical diagnosis of central nervous system demyelination

C Tiller, LJ Black, AL Ponsonby, B Taylor… - The Journal of Steroid …, 2022 - Elsevier
… of a first clinical diagnosis of CNS demyelination (… low sun exposure and low serum 25-hydroxyvitamin
D (25(OH)D) concentrations were independent risk factors for a first demyelinating

Nutritional factors and aging in demyelinating diseases

AM Adamo - Genes & nutrition, 2014 - Springer
… In the CNS, demyelination is usually a consequence of OL … case sunlight is essential to the
conversion of pre-vitamin D3 to active … model of demyelination in rats, which is independent of …