Superhydrophobic polyurethane foam is one of the most promising materials for oil-water separation. However, there are only limited studies prepared matrix superhydrophobic foams as adsorbents. In this paper, SiO₂ modified by 1H, 1H, 2H, 2H-perfluorododecyl trichlorosilane (F-SiO₂) was added into the lignin-based foam matrix by a one-step foaming technique. The average diameter of F-SiO₂ was about 480 nm with an water contact angle (WCA) of 160.3°. The lignin-based polyurethane foam with F-SiO₂ had a superhydrophobic water contact angle of 151.3°. There is no obvious change in contact angle after 100 cycles of compression or after cutting and abrasion. Scanning electron microscopy (SEM) analysis showed that F-SiO₂ was distributed both on the surface and inside of the foam. The efficiency for oil-water separation reached 99 %. Under the light intensity of 1 kW/m², the surface temperature of the lignin-based foam rose to 77.6 °C. In addition, the foam exhibited self-cleaning properties and degraded within 2 h in an alcoholic alkali solution. Thus, in this study, we developed a novel matrix superhydrophobic lignin-based polyurethane foam with an excellent promise to be used as oil water separation adsorbents in industrial wastewater treatment and oil spill clean-up processes.